Pediatric Cancer

Stem cell transplant

Antibody Aimed at Monocytes in Graft-versus-host Disease

Phase 2 trial of the monoclonal antibody Axatilimab shows modest doses attenuate symptoms.

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Latest in Pediatric Cancer

Child Chemotherapy Patient Finishing Treatment with a Ceremonial Bell Ring

Preserving Fertility Options After Treatment is Advocates’ Goal

Call-to-action urges preservation of reproduction as part of pediatric cancer care protocols.
Mitochondrial DNA in a ring accurately predicting gene function

Mitochondrial Transport Tracked by Innovative GeneMAP

Researchers design GeneMAP en route to defining biological function of “orphan” protein.

Questionable Value of Fungal Disease Test

Study exposes low utility of sinus CT, the most common test given to febrile neutropenic pediatric patients with cancer.
A young girl of African descent is indoors in a hospital room. She has cancer. She is lying in bed with her teddy bear while hooked up to an IV. She is looking at the camera.

Strategy Trims Antibiotic Use in Pediatric Cancer Patients

Risk-prediction models inform antibiotic use in non-neutropenic patients – and now a new cancer population.
Nurse reassures girl lying down in an MRI machiine

Silent Cerebral Infarct Complicates Sickle Cell

Preventing these small brain injuries in childhood can improve cognitive functioning and help adults avoid major strokes.
Mother holds young girl on hip, touching her forehead. Both are wearing surgical masks.

T-to-A Metric for Fever Fails Scrutiny

Large study results argue against time-prescribed antibiotics for febrile children with cancer.
Black boy in white tank top at the doctor getting his heart checked

School-Age Children with Sickle Cell Face Nutritional Challenge

Underweight children show increased risk of early mortality from early in life.
illustration of mitosis in shades of red/pink

Mutated DNA Regulator Implicated in Cancer Cell Development

Studies on SETD2 identified correlations between mutated chromosomes in cancer cells and chemotherapy resistance.
Peds ultrasound

Intraoperative Ultrasound Proves Merit in Pediatric Setting

A case study of a patient with multiple endocrine neoplasia demonstrates the synergy of new surgical techniques and technology in a minimally invasive operation.