New research from microbiologist Maria Hadjifrangiskou, Ph.D., and colleagues at Vanderbilt University Medical Center suggests a novel mechanism – and potential new therapeutic targets — for urinary tract infections.
The mechanism is based on the discovery that uropathogenic E. coli can import the elements to make ammonia and overcome acid-resistence.
"Our study is the first to examine acid tolerance in uropathogenic E. coli and lays the foundation for targeted antibacterial therapies," Hadjifrangiskou said.
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